I'm a long time fan of the Fallout series, but after Fallout 3 I'm wary about trying this one for the PC.
Depending what your pc specs are if your machine is nice and powerful or old, If its powerful you shouldn't have any problems if its an older beast I'de definitely get it on one of the consoles.
I'm hearing a lot of negatives from the xbox version but none for the ps3.
A large majority of the people complaining about pc problems are trying to run it on crappy pc's lol and they want to just blame the game not there hardware.
I still get a random crash here and there but I don't think its the games fault its more got something to do with the latest Catalyst drivers which I have been having problems with other games as well.